A request for review of continuing research should include a protocol summary and a status report on the progress of the research including:

• the number of subjects accrued;
• a summary of any unanticipated problems and available information regarding adverse events (in many cases, such a summary could be a simple brief statement that there have been no unanticipated problems and that adverse events have occurred at the expected frequency and level of severity as documented in the research protocol, the informed consent document, and any investigator brochure);
• a summary of any withdrawal of subjects from the research since the last IRB review;
• a summary of any complaints about the research since the last IRB review;
• a summary of any recent literature that may be relevant to the research and any amendments or modifications to the research since the last IRB review;
• any relevant multi-center trial reports;
• any other relevant information, especially information about risks associated with the research; and
• a copy of the current informed consent document and any newly proposed consent document.

Requests for annual review may be submitted to the Office of Research, Room 308, Old Main or via email to amiller@uwyo.edu.